Drug Usage – The person gains superpowers via drugs.
Bane (DC) uses the drug Venom to gain superhuman strength in Batman V1 #497.
Hourman (DC) take the drug Miraclo to gain superpowers for an hour in DC Who’s Who V1 #10.
There have been attempts to deal with drugs realistically in comic books.
Harry Osborn (Marvel) struggles with drug addiction in Marvel Fact Files #29(Eaglemoss).
Speedy (DC) is shown as a drug addict in Green Lantern V2 #85.